The Wise River is a major tributary of the Big Hole River, flowing through the Pioneer Mountains near the town of Wise River. The stream holds brook trout, brown trout, and Arctic grayling in its upper reaches, adding to the Big Hole's importance as Montana's last stronghold for grayling in the lower 48. This is intimate wade fishing through beautiful mountain meadows. Grayling must be released. The Wise River valley provides a scenic backdrop for anglers seeking native fish in uncrowded water. Best fishing is summer through early fall. The town of Wise River offers basic services.