The St. Regis River flows through the town of St. Regis in western Montana, joining the Clark Fork near I-90. The river holds rainbow, brown, and brook trout, with some cutthroat in upper reaches. Access is good along the highway corridor. The St. Regis offers pleasant small-river fishing without the crowds of more famous waters. Summer provides the best conditions. The river sees recreational floating pressure but remains a solid fishing option for anglers passing through on Interstate 90.